TRIM22 antibody

Catalog No. ABIN7120277

The Rabbit Polyclonal anti-TRIM22 antibody has been validated for WB and ELISA. It is suitable to detect TRIM22 in samples from Human and Mouse.

Quick Overview for TRIM22 antibody (ABIN7120277)

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRIM22 Antibody

Purpose: TRIM22 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tripartite motif-containing 22

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Alternative Name: TRIM22

Background:

Synonyms: E3 ubiquitin-protein ligase TRIM22|50 kDa-stimulated trans-acting factor|RING finger protein 94|RING-type E3 ubiquitin transferase TRIM22|Staf-50|Tripartite motif-containing protein 22|TRIM22|RNF94|STAF50

Background: Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus(EMCV) and hepatitis B virus(HBV). Acts as a transcriptional repressor of HBV core promoter. May have E3 ubiquitin-protein ligase activity.

Molecular Weight: 52 kDa

Gene ID: 10346

UniProt: Q8IYM9